June 14, 2020
Supplementary data 4. Association of the 13 secretory hub-like molecules with activation of T cells and/or macrophages and anti-inflammation.
Dynamic Transcriptome Analysis Unveils Key Pro-Resolving Factors of Chronic Inflammatory Arthritis
For each regulator, Entrez ID, gene name, description, and cluster to which it belongs are shown in the table. The previously reported associations with activation of the cells and anti-inflammatory functions are described together with the references.
June 14, 2020
Supplementary data 3. Key regulator candidates identified from a resolution-associated network model.
Dynamic Transcriptome Analysis Unveils Key Pro-Resolving Factors of Chronic Inflammatory Arthritis
For each of the 85 hub-like molecules, Entrez ID, gene name, description, and cluster to which it belongs are shown together with its degree, betweenness, and closeness centralities, as well as the significance of the individual centralities (p value) in the resolution-associated network. In addition, differential expression patterns of the molecules in P/I and R/P (“Up” or “Down”) and secretory proteins reported previously in the plasma proteome (“secreted”) are shown.
June 14, 2020
Supplementary data 2. Differentially expressed genes (DEGs) from the comparisons of P/I and R/P.
Dynamic Transcriptome Analysis Unveils Key Pro-Resolving Factors of Chronic Inflammatory Arthritis
For each DEG, whether the DEG was up- (Up) or down-regulated (Down) in the two comparisons is shown, together with its log2-fold-changes and overall p values. For the DEG, Entrez ID, gene name, description, and clusters to which they belonged are also shown.
June 14, 2020
Supplementary data 1. GOBPs enriched by the DEGs in the six clusters.
Dynamic Transcriptome Analysis Unveils Key Pro-Resolving Factors of Chronic Inflammatory Arthritis
For each cluster (C1-6), GOBPs significantly (p ≤ 0.05 and number of genes > 3) enriched by the DEGs in the cluster are shown, together with the numbers of DEGs involved in the corresponding GOBPs (Count) and the enrichment p values.
March 14, 2018
DEG table NFAT5 deficient RA-FLSs and MEFs
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Lists of differentially expressed genes (DEGs) from the comparison of NFAT5 siRNA-treated RA-FLSs versus control siRNA-treated RA-FLSs and Nfat5+/+ mouse embryonic fibroblasts (MEFs) versus Nfat5-/- MEFs. Supplementary data for "Transcription Factor NFAT5 Promotes Migration and Invasion of Rheumatoid Synoviocytes via Coagulation Factor III and C-C motif chemokine ligand 2", Journal of Immunology.
March 14, 2018
DEG table RAFLS vs OAFLS
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Lists of differentially expressed genes (DEGs) from comparison of RA-FLSs or RA-FLSs-stimulated with IL-1 beta versus OA-FLSs. Supplementary data for "Transcription Factor NFAT5 Promotes Migration and Invasion of Rheumatoid Synoviocytes via Coagulation Factor III and C-C motif chemokine ligand 2", Journal of Immunology.
March 14, 2018
cell migration invasion-related DEGs in RA-FLSs
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Lists of cell migration/invasion-related differentially expressed genes (DEGs) in RA-FLSs. Supplementary data for "Transcription Factor NFAT5 Promotes Migration and Invasion of Rheumatoid Synoviocytes via Coagulation Factor III and C-C motif chemokine ligand 2", Journal of Immunology.
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